Invitrogen

SET Polyclonal Antibody

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SET Antibody (PA5-17962) in WB

Western blot was performed using Anti-SET Polyclonal Antibody (Product # PA5-17962) and a 38 kDa corresponding to SET was observed across cell lines tested except MCF 10A. The expression of SET is low in MCF 10A when compared to MCF-7 and MDA-MB-231 as it is overexpressed in breast cancers. Whole cell extracts (30 µg lysate) of HeLa (Lane 1), MCF-7 (Lane 2), MDA-MB-231 (Lane 3), MOLT-4 (Lane 4), Jurkat (Lane 5) and MCF 10A (Lane 6) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were t... View More

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SET Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SET in Human Adrenal Gland using a SET monoclonal antibody (Product #PA5-17962) at 3.75 µg/mL. The Human Adrenal Gland tissue section was paraffin embeded and detected using steamed antigen retrieval with citrate buffer pH 6, AP-staining.

产品信息

PA5-17962

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.3-1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide sequence (SAPAAKVSKKELNS) corresponding to the N-terminus amino acids of SET

偶联物

Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Antigen affinity chromatography

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_10984416

产品详细信息

This antibody is predicted to react with bovine based on sequence homology.

靶标信息

SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: HLA-DR-associated protein II; I IGAAD; I-2PP2A; IGAAD; Inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; OTTHUMP00000022286; PHAPII; Phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor; Protein SET; RP11-216B9.3; SET nuclear oncogene; SET translocation (myeloid leukemia-associated); TAF-1a; TAF-1b; TAF-I; Template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor

基因别名: 2PP2A; I2PP2A; IGAAD; IPP2A2; PHAPII; SET; TAF-I; TAF-IBETA

UniProt ID: (Human) Q01105

Entrez Gene ID: (Human) 6418

分子生物学功能: chromatin/chromatin-binding, or -regulatory protein