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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SEB; SET binding protein 1; SET-binding protein
基因别名: KIAA0437; MRD29; SEB; SETBP1
UniProt ID: (Human) Q9Y6X0
Entrez Gene ID: (Human) 26040, (Rat) 291423
分子生物学功能:
histone modifying enzyme