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Proteintech
SETDB1 Monoclonal Antibody (1H6E5), CoraLite® Plus 488
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产品信息
CL488-66293
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1H6E5
抗原
SETDB1 fusion protein Ag21644
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: MSSLPGCIG LDAATATVES EEIAELQQAV VEELGISMEE LRHFIDEELE KMDCVQQRKK QLAELETWVI QKESEVAHVD QLFDDASRAV TNCESLVKDF YSKLGLQYRD SSSEDESSRP TEIIEIPDED DDVLSIDSGD AGSRTPKDQK LREAMAALRK SAQDVQKFMD AVNKKSSSQD LHKGTLSQMS GELSKDGDLI VSMRILGKKR TKTWHKGTLI AIQTVGPGKK YKVKFDNKGK SLLSGNHIAY DYHPPADKLY VGSRVVAKYK DGNQVWLYAG IVAETPNVKN KLRFLIFFDD GYASYVTQSE LYPICRPLKK TWEDIEDISC RDFIEEYVTA YPNRPMVLLK S
靶标信息
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ERG-associated protein with a SET domain, ESET; ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; Histone H3-K9 methyltransferase 4; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SET domain ERG-associated histone methyltransferase; SET domain, bifurcated 1; tudor domain containing 21
基因别名: AU022152; ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; mKIAA0067; SETDB1; TDRD21
UniProt ID: (Human) Q15047
Entrez Gene ID: (Human) 9869, (Mouse) 84505, (Rat) 689883
transcription, DNA-templated
Ras protein signal transduction
response to vitamin
histone lysine methylation
response to ethanol
positive regulation of methylation-dependent chromatin silencing
negative regulation of transcription from RNA polymerase II promoter
inner cell mass cell proliferation
regulation of transcription, DNA-templated
chromatin modification
methylation
histone H3-K9 trimethylation
bone development
