Invitrogen

SFRP2 (soluble) Polyclonal Antibody

查看其他11个SFRP2抗体

问题与答案

问题与答案

问题与答案

Immunogen image

SFRP2 (soluble) Polyclonal Antibody

Immunogen Image SFRP2 (soluble) Polyclonal Antibody

产品信息

PA5-148479

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1 µg/mL

-

产品规格

种属反应

Mouse

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Mouse myeloma cell line NS0-derived recombinant mouse sFRP-2 (R&D Systems, Catalog # 1169-FR), Leu25-Cys295

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with trehalose

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: FRP 2; MGC128911; MGC153618; MGC53344; Protein SDF5; SARP 1; SARP-1; SDF 5; Secreted apoptosis-related protein 1; Secreted frizzled-related protein 2; secreted frizzled-related sequence protein 2; secreted frizzled-related sequence protein 5; sFRP 2; sFRP-2; Sfrp2 protein; stromal cell derived factor 5

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基因别名: AI851596; Sarp1; Sdf5; Sfrp2

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UniProt ID: (Mouse) P97299

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Entrez Gene ID: (Mouse) 20319

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protein binding enzyme activator activity Wnt-protein binding receptor agonist activity endopeptidase activator activity transmembrane signal receptor

patterning of blood vessels somitogenesis neural tube closure chondrocyte development outflow tract morphogenesis cardiac left ventricle morphogenesis apoptotic process signal transduction multicellular organism development positive regulation of cell proliferation negative regulation of cell proliferation male gonad development anterior/posterior pattern specification negative regulation of gene expression negative regulation of cardiac muscle cell apoptotic process negative regulation of epithelial to mesenchymal transition positive regulation of endopeptidase activity Wnt signaling pathway neural tube development regulation of Wnt signaling pathway cell differentiation negative regulation of Wnt signaling pathway collagen fibril organization positive regulation of cell growth negative regulation of cell growth negative regulation of cell migration negative regulation of BMP signaling pathway cellular response to extracellular stimulus positive regulation of peptidyl-serine phosphorylation positive regulation of catenin import into nucleus post-anal tail morphogenesis regulation of cell proliferation response to drug negative regulation of mesodermal cell fate specification embryonic digit morphogenesis regulation of apoptotic process positive regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of JUN kinase activity positive regulation of fat cell differentiation positive regulation of osteoblast differentiation positive regulation of angiogenesis negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter development of primary male sexual characteristics digestive tract morphogenesis negative regulation of epithelial cell proliferation negative regulation of peptidyl-tyrosine phosphorylation cartilage development convergent extension involved in axis elongation canonical Wnt signaling pathway bone morphogenesis negative regulation of dermatome development hematopoietic stem cell proliferation cellular response to X-ray negative regulation of canonical Wnt signaling pathway regulation of establishment of planar polarity planar cell polarity pathway involved in neural tube closure Wnt signaling pathway involved in somitogenesis positive regulation of canonical Wnt signaling pathway negative regulation of extrinsic apoptotic signaling pathway via death domain receptors regulation of stem cell division negative regulation of planar cell polarity pathway involved in axis elongation positive regulation of receptor activity