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Proteintech
SFRS8 Polyclonal Antibody
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产品信息
24705-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SFRS8 Fusion Protein Ag19762 (600-951 aa encoded by BC136678)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody detects 130-150 kDa SFRS8 protein.
Immunogen sequence: LDDDSDDDE ESKEGQESSS SAANTNPAVA PPCVVVEEKK PQLTQEELEA KQAKQKLEDR LAAAAREKLA QASKESKEKQ LQAERKRKAA LFLQTLKNPL PEAEAGKIEE SPFSVEESST TPCPLLTGGR PLPTLEVKPP DRPSSKSKDP PREEEKEKKK KKHKKRSRTR SRSPKYHSSS KSRSRSHSKA KHSLPSAYRT VRRSRSRSRS PRRRAHSPER RREERSVPTA YRVSRSPGAS RKRTRSRSPH EKKKKRRSRS RTKSKARSQS VSPSKQAAPR PAAPAAHSAH SASVSPVESR GSSQERSRGV SQEKEAQISS AIVSSVQSKI TQDLMAKVRA MLAASKNLQT SAS (600-951 aa encoded by BC136678)
靶标信息
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Splicing factor, arginine/serine-rich 8; splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila); splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, Drosophila homolog); splicing factor, suppressor of white-apricot family; Splicing factor, suppressor of white-apricot homolog; Suppressor of white apricot protein homolog
基因别名: SFRS8; SFSWAP; SWAP
UniProt ID: (Human) Q12872
Entrez Gene ID: (Human) 6433
