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Proteintech
SGEF Polyclonal Antibody
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产品信息
12493-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SGEF Fusion Protein Ag3198 (1-301 aa encoded by BC016628)
偶联物
形式
Liquid
浓度
0.14 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MISFLILPM QRVTRLPLLM DTICQKTPKD SPKYEVCKRA LKEVSKLVRL CNEGARKMER TEMMYTINSQ LEFKIKPFPL VSSSRWLVKR GELTAYVEDT VLFSRRTSKQ QVYFFLFKDV LIITKKKSEE SYNVNDYSLR DQLLVESCDN EELNSSPGKN SSTMLYSRQS SASHLFTLTV LSNHANEKVE MLLGAETQSE RARWITALGH SSGKPPADRT SLTQVEIVRS FTAKQPDELS LQVADVVLIY QRVSDGWYEG ERLRDGERGW FPMECAKEIT CQATIDKNVE RMGRLLGLET NV (1-301 aa encoded by BC016628)
靶标信息
Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Rho guanine nucleotide exchange factor (GEF) 26; Rho guanine nucleotide exchange factor 26; SH3 domain-containing guanine exchange factor; Src homology 3 domain-containing guanine nucleotide exchange factor; testicular tissue protein Li 171
基因别名: ARHGEF26; CSGEF; HMFN1864; SGEF
UniProt ID: (Human) Q96DR7
Entrez Gene ID: (Human) 26084
