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Invitrogen
SGEF Polyclonal Antibody
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产品信息
PA5-65547
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human SGEF
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: ESEVDNDVDSP GSLRRGLRST SYRRAVVSGF DFDSPTSSKK KNRMSQPVLK VVMEDKEKFS SLGRIKKKML KGQGTFDGEE NAVLYQNYKE KALDIDSDEE SEPKEQKSDE KIVIHHKPLR STWSQLSAVK RKGLSQ
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 95%.
靶标信息
Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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