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Invitrogen
SGK2 Polyclonal Antibody
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SGK2 Antibody (PA5-88372) in WB
Western blot analysis of SGK2 in extracts of various cell lines. Samples were incubated with SGK2 Polyclonal antibody (Product # PA5-88372) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-88372
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 228-367 of human SGK2 (NP_7337941)
偶联物
形式
Liquid
浓度
0.41 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LHGLPPFYSQ DVSQMYENIL HQPLQIPGGR TVAACDLLQS LLHKDQRQRL GSKADFLEIK NHVFFSPINW DDLYHKRLTP PFNPNVTGPA DLKHFDPEFT QEAVSKSIGC TPDTVASSSG ASSAFLGFSY APEDDDILDC; Positive Samples: BxPC-3, 293T; Cellular Location: Cytoplasm, Nucleus
靶标信息
SGK2 is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Although little is known about the transcriptional regulation of SGK2, the protein has been shown to be phosphorylated and activated by 3 phosphoinositide dependent protein kinase 1 (PDK1), and to a lesser extent insulin like growth factor 1, in vitro.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; Serum/glucocorticoid-regulated kinase 2
基因别名: dJ138B7.2; H-SGK2; SGK2
UniProt ID: (Human) Q9HBY8
Entrez Gene ID: (Human) 10110
regulation of cell growth
protein phosphorylation
cellular sodium ion homeostasis
response to oxidative stress
positive regulation of sodium ion transport
peptidyl-serine phosphorylation
positive regulation of transporter activity
ion transmembrane transport
intracellular signal transduction
regulation of cell proliferation
regulation of apoptotic process
