Proteintech

SH3BP4 Polyclonal Antibody

Name: SH3BP4 Polyclonal Antibody
Brand: Proteintech
SKU: 17691-1-AP

3 篇参考文献

查看其他7个SH3BP4抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)

SH3BP4 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 6

SH3BP4 Antibody (17691-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 17691-1-AP (SH3BP4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

SH3BP4 Antibody in Immunoprecipitation (IP)

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Immunogen image

Immunogen Image SH3BP4 Polyclonal Antibody

产品信息

17691-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看2篇已发表文章 2篇已发表文章

免疫细胞化学 (ICC/IF)

1:20-1:200

免疫沉淀 (IP)

0.5-4.0 µg

不适用 (N/A)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

SH3BP4 Fusion Protein Ag11847 (615-963 aa encoded by BC057396)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.18 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: SAIKPSGQR RFLKKNEVGK IILSPFATTT KYPTFQDRPV SSLKFGKLLK TVVRQNKNHY LLEYKKGDGI ALLSEERVRL RGQLWTKEWY IGYYQGRVGL VHTKNVLVVG RARPSLCSGP ELSTSVLLEQ ILRPCKFLTY IYASVRTLLM ENISSWRSFA DALGYVNLPL TFFCRAELDS EPERVASVLE KLKEDCNNTE NKERKSFQKE LVMALLKMDC QGLVVRLIQD FVLLTTAVEV AQRWRELAEK LAKVSKQQMD AYESPHRDRN GVVDSEAMWK PAYDFLLTWS HQIGDSYRDV IQELHLGLDK MKNPITKRWK HLTGTLILVN SLDVLRAAAF SPADQDDFVI (615-963 aa encoded by BC057396)

靶标信息

SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.

仅用于科研。不用于诊断过程。未经明确授权不得转售。