Rockland

SH3BP4 Polyclonal Antibody

Name: SH3BP4 Polyclonal Antibody
Brand: Rockland
SKU: 600-401-EH7

查看其他7个SH3BP4抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

SH3BP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

SH3BP4 Antibody (600-401-EH7) in IHC (P)

Immunohistochemistry of SH3BP4 antibody. Tissue: Human lung tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: SH3BP4 antibody at 5 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: SH3BP4 is nuclear and cytoplasmic. Staining: SH3BP4 as precipitated blue signal with brown nuclear coun... View More

Product Image Gallery

Immunogen image

Immunogen Image SH3BP4 Polyclonal Antibody

产品信息

600-401-EH7

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

免疫组化（石蜡） (IHC (P))

5 µg/mL

酶联免疫吸附实验 (ELISA)

1:10,000-1:20,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Anti-SH3BP4 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide from near the C-terminus of human SH3BP4.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.

仅用于科研。不用于诊断过程。未经明确授权不得转售。