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Proteintech
SH3GL2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
12435-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SH3GL2 Fusion Protein Ag3114 (1-279 aa encoded by BC032825)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.28 mg/mL
规格
42 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSVAGLKKQ FHKATQKVSE KVGGAEGTKL DDDFKEMERK VDVTSRAVME IMTKTIEYLQ PNPASRAKLS MINTMSKIRG QEKGPGYPQA EALLAEAMLK FGRELGDDCN FGPALGEVGE AMRELSEVKD SLDIEVKQNF IDPLQNLHDK DLREIQHHLK KLEGRRLDFD YKKERQGKIP DEELRQALEK FDESKEIAES SMFNLLEMDI EQVSQLSALV QAQLEYHKQA VQILQQVTVR LEERIRQASS QPRREYQPKP RMSLEFPTGD STQPNGGLSH (1-279 aa encoded by BC032825)
靶标信息
Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: bA335L15.1; bA335L15.1 (SH3-domain GRB2-like 2); contains SH3 domain; endophilin; Endophilin A1 BAR domain; endophilin I; endophilin-1; FLJ20276; FLJ25015; SH3 domain protein 2A; SH3 domain-containing GRB2-like 2; SH3 domain-containing GRB2-like protein 2; SH3-domain GRB2-like 2; SH3GL2; SH3p4; similar to endophilin 1; unnamed protein product
基因别名: 9530001L19Rik; B930049H17Rik; CNSA2; EEN-B1; EEN1; SH3D2A; SH3P4; SH3PA
UniProt ID: (Human) Q99962, (Rat) O35179, (Mouse) Q62420
Entrez Gene ID: (Human) 6456, (Rat) 116743, (Mouse) 20404
signal transduction
central nervous system development
negative regulation of gene expression
neuron projection development
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of MAPK cascade
synaptic vesicle endocytosis
dendrite extension
membrane tubulation
postsynaptic actin cytoskeleton organization
negative regulation of blood-brain barrier permeability
cellular response to brain-derived neurotrophic factor stimulus
regulation of receptor internalization
regulation of endocytosis
lipid tube assembly
membrane bending
vesicle scission
positive regulation of membrane tubulation
regulation of clathrin-mediated endocytosis
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