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Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (90%), Rat (88%), Bovine (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase SH3RF1; FLJ21602; plenty of SH3 domains; Plenty of SH3s; Protein POSH; putative E3 ubiquitin-protein ligase SH3RF1; RING finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3 multiple domains protein 2
基因别名: KIAA1494; POSH; POSH1; RNF142; SH3MD2; SH3RF1
UniProt ID: (Human) Q7Z6J0
Entrez Gene ID: (Human) 57630