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Proteintech
SHKBP1 Polyclonal Antibody
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产品信息
12703-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SHKBP1 Fusion Protein Ag3386 (358-707 aa encoded by BC022855)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MKDNDLLVS ELYRDPAEDG VTALSVYLTP KTSDSGNWIE IAYGTSSGGV RVIVQHPETV GSGPQLFQTF TVHRSPVTKI MLSEKHLISV CADNNHVRTW SVTRFRGMIS TQPGSTPLAS FKILALESAD GHGGCSAGND IGPYGERDDQ LVFIQKVVPS ASQLFVRLSS TGQRVCSVRS VDGSPTTAFT VLECEGSRRL GSRPRRYLLT GQANGSLAMW DLTTAMDGLG QAPAGGLTEQ ELMEQLEHCE LAPPAPSAPS WGCLPSPSPR ISLTSLHSAS SNTSLSGHRG SPSPPQAEAR RRGGGSFVER CQELVRSGPD LRRPPTPAPW PSSGLGTPLT PPKMKLNETS F (358-707 aa encoded by BC022855)
靶标信息
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SETA binding protein 1; SETA-binding protein 1; SH3KBP1-binding protein 1
基因别名: B930062H15Rik; PP203; RGD1309281; SB1; SHKBP1
UniProt ID: (Human) Q8TBC3, (Rat) P0C5J9, (Mouse) Q6P7W2
Entrez Gene ID: (Human) 92799, (Rat) 292735, (Mouse) 192192
