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Immunogen sequence: PVFPVKRRNR HSLVGPQQLG GRPAPVRRSN TMPPNLGNAG LLGRMLDEKT PPSPSGQPEE PGMVRLVCGH HNWIAVAYTQ FLVCYRLKEA
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 94%.
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SETA-binding protein 1; SH3KBP1-binding protein 1
基因别名: PP203; SB1; SHKBP1
UniProt ID: (Human) Q8TBC3
Entrez Gene ID: (Human) 92799
分子生物学功能: scaffold/adaptor protein