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Invitrogen
SHMT1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-88581
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.51 mg/mL
规格
151 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FKVYQHQVVA NCRALSEALT ELGYKIVTGG SDNHLILVDL RSKGTDGGRA EKVLEACSIA CNKNTCPGDR SALRPSGLRL GTPALTSRGL LEKDFQKVAH FIHRGIELTL QIQSDTGVRA TLKEFKERLA GDKYQAAVQA LREEVESFAS LFPLPGLPDF; Positive Samples: 293T, HepG2, HT-29, K-562, A375, Mouse liver; Cellular Location: Cytoplasm
靶标信息
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: F20D10.50; F20D10_50; Glycine hydroxymethyltransferase; MGC15229; MGC24556; SERINE HYDROXYMETHYLTRANSFERASE 1; Serine hydroxymethyltransferase, cytosolic; Serine methylase; SERINE TRANSHYDROXYMETHYLASE; SERINE TRANSHYDROXYMETHYLTRANSFERASE; serine transhydroxymethyltransferase 1; SHM1; SHMT; STM
基因别名: AI324848; AI385541; C81125; LRRGT00032; mShmt; mshmt1; mshmt2; Shmt; Shmt1
UniProt ID: (Mouse) P50431
Entrez Gene ID: (Mouse) 20425, (Rat) 287379
glycine metabolic process
glycine biosynthetic process
L-serine metabolic process
L-serine catabolic process
one-carbon metabolic process
purine nucleobase biosynthetic process
glycine biosynthetic process from serine
folic acid metabolic process
protein tetramerization
protein homotetramerization
tetrahydrofolate interconversion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
