Abnova

SHOX2 Monoclonal Antibody (1D1)

Name: SHOX2 Monoclonal Antibody (1D1)
Brand: Abnova
SKU: H00006474-M01J

查看其他6个SHOX2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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SHOX2 Antibody (H00006474-M01J) in WB

SHOX2 monoclonal antibody (M01J), clone 1D1. Western Blot analysis of SHOX2 expression in HeLa.

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产品信息

H00006474-M01J

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

功能检测 (Functional)

1-5 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

1D1

抗原

SHOX2 (NP_006875, 117 a.a. approximately 204 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Cell lysate).

Immunogen sequence: SPELKDRKDD AKGMEDEGQT KIKQRRSRTN FTLEQLNELE RLFDETHYPD AFMREELSQR LGLSEARVQV WFQNRRAKCR KQENQLHK

Cell culture grade monoclonal antibodies are obtained by purifying "hybridoma culture medium" which completely eliminates any contamination of mice. They have high affinity, high purity, and no contamination.

靶标信息

SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Homeobox protein Og12X; OG-12; OGI2X; Paired family homeodomain protein Prx3; Paired-related homeobox protein SHOT; Short stature homeobox protein 2; SHOX homologous gene on chromosome 3

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基因别名: 6330543G17Rik; OG12; OG12X; Prx3; SHOT; SHOX2

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UniProt ID: (Human) O60902, (Mouse) P70390, (Rat) O35750

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Entrez Gene ID: (Human) 6474, (Mouse) 20429, (Rat) 25546

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功能

sequence-specific DNA binding DNA binding homeodomain transcription factor

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