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Invitrogen
SHROOM3 Polyclonal Antibody
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SHROOM3 Antibody (PA5-61589)
Relative expression in different tissues in IHC: Detection of differential expression levels of SHROOM3 demonstrates antibody specificity. Immunohistochemical analysis of SHROOM3 using anti-SHROOM3 Polyclonal Antibody (Product # PA5-61589), shows significant staining of SHROOM3 in human rectum and shows minimal or weak staining in human skeletal muscle tissues. The relative expression levels of SHROOM3 wit... View More
产品信息
PA5-61589
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human SHROOM3
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: EEGTRKRVSL PQWPPPSRAK WAHAAREDSL PEESSAPDFA NLKHYQKQQS LPSLCSTSDP DTPLGAPSTP GRISLRISES VLRDSPPPHE DYEDEVF
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.
靶标信息
SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM3 is an actin-binding protein is a regulator of the microtubule cytoskeleton during epithelial morphogenesis and is sufficient and necessary to induce a redistribution of the microtubule regulator gamma-tubulin. It is necessary for both apiscobasal cell elongation and apical constriction in the neural epithelium. SHROOM3 has also been shown to be essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription relying on the Pitx1 transcription factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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