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Invitrogen
SIGLEC16 Monoclonal Antibody (706045)
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产品信息
MA5-61722
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
706045
抗原
Human Siglec-16 peptide
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
SIGLEC16 (Sialic Acid Binding Ig Like Lectin 16) is a gene that encodes a member of the Siglec family of proteins, which are primarily expressed on the surface of immune cells such as macrophages, dendritic cells, and certain types of lymphocytes. These proteins are involved in the recognition of sialic acid-containing glycan structures on the surface of cells, playing a crucial role in cell-cell interactions and immune regulation. SIGLEC16, in particular, is thought to participate in modulating immune responses and maintaining immune homeostasis. It can influence processes such as inflammation, phagocytosis, and the inhibition of immune cell activation. The expression and function of SIGLEC16 can vary among individuals due to genetic polymorphisms, which may impact susceptibility to infections and autoimmune diseases. Understanding the specific roles and mechanisms of SIGLEC16 in immune regulation is important for developing therapeutic strategies aimed at modulating immune responses in various diseases, including inflammatory and autoimmune conditions. Research into SIGLEC16 also provides insights into the broader functions of the Siglec family and their potential as targets for immunotherapy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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