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产品信息
HA500463
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within mouse six2a aa 100-150/291.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 0.2% BSA, 50% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
靶标信息
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Homeobox protein SIX2; Sine oculis homeobox homolog 2; sine oculis-related homeobox 2 homolog
基因别名: SIX2
UniProt ID: (Human) Q9NPC8, (Mouse) Q62232
Entrez Gene ID: (Human) 10736, (Mouse) 20472, (Rat) 366542
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein complex binding
DNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
kidney development
chondrocyte differentiation
mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription from RNA polymerase II promoter
protein import into nucleus
mesodermal cell fate specification
cell proliferation
anatomical structure morphogenesis
anterior/posterior axis specification
cell migration
regulation of ossification
regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
nephron development
nephron morphogenesis
mesenchymal stem cell maintenance involved in nephron morphogenesis
mesenchymal cell differentiation involved in kidney development
regulation of branching involved in ureteric bud morphogenesis
mesenchymal stem cell proliferation
positive regulation of chondrocyte proliferation
metanephros development
regulation of transcription, DNA-templated
multicellular organism development
embryonic skeletal system morphogenesis
