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Proteintech
SLAIN2 Polyclonal Antibody
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产品信息
13908-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SLAIN2 Fusion Protein Ag4888 (231-581 aa encoded by BC040993)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PGNSGNLKS SDRNPPLSPQ SSIDSELSAS ELDEDSIGSN YKLNDVTDVQ ILARMQEESL RQEYAATTSR RSSGSSCNST RRGTFSDQEL DAQSLDDEDD NMHHAVYPAV NRFSPSPRNS PRPSPKQSPR NSPRSRSPAR GIEYSRVSPQ PMISRLQQPR LSLQGHPTDL QTSNVKNEEK LRRSLPNLSR TSNTQVDSVK SSRSDSNFQV PNGGIPRMQP QASAIPSPGK FRSPAAPSPL ALRQPVKAFS NHGSGSPGSQ EITQLTQTTS SPGPPMVQST VSANPPSNIN SATLTRPAGT TAMRSGLPRP SAPSAGGIPV PRSKLAQPVR RSLPAPKTYG SMKDDSWKDG CY (231-581 aa encoded by BC040993)
靶标信息
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ21611; SLAIN motif family, member 2; SLAIN motif-containing protein 2
基因别名: 5033405K12Rik; 8030444K12Rik; AI596370; KIAA1458; RGD1311593; SLAIN2
UniProt ID: (Human) Q9P270, (Mouse) Q8CI08
Entrez Gene ID: (Human) 57606, (Rat) 305310, (Mouse) 75991
