Positive Control: mouse brain
Predicted Reactivity: Human (100%), Rhesus Monkey (97%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
蛋白别名: Dct-1; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; microcytic anemia, viable anaemia; Natural resistance-associated macrophage protein 2; NRAMP 2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2
基因别名: AHMIO1; DCT1; DMT1; mk; NRAMP2; OK/SW-cl.20; SLC11A2; van
分子生物学功能: secondary carrier transporter