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Invitrogen
SLC16A3 Polyclonal Antibody
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SLC16A3 Antibody (PA5-111848) in WB
Western Blot analysis of SLC16A3 was performed in human K562 chronic myelogenous leukemia cell line lysate (lanes 1 and 3) and human MDA-MB-231 breast adenocarcinoma cell line lysate (lanes 2 and 4). Lane 1,2: SLC16A3 Antibody (Product # PA5-111848) at a dilution of 1:200. Lane 3,4: SLC16A3 Antibody preincubated with the negative control antigen.
产品信息
PA5-111848
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 447-459 of rat MCT4 (Intracellular, C-terminus)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)REVEHFL KAEPEK
Homology: Mouse, human amino acid residues are identical.
靶标信息
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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