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SLC19A1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
BS-20879R
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from mouse SLC19A1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: folate transporter 1; IFC-1; intestinal folate carrier 1; intestinal folate carrier protein; methotrexate carrier 1; methotrexate carrier 2; methotrexate carrier 5; methotrexate carrier 6; organic anion transporter; plasma membrane folate antiporter SLC19A1; reduced folate carrier 1; RFC-1; RFC1; solute carrier family 19 (folate transporter), member 1; solute carrier family 19 (sodium/hydrogen exchanger), member 1; solute carrier family 19 member 1; unnamed protein product
基因别名: MTX-1; MTX1; RFC; RFC-1; RFC1
UniProt ID: (Mouse) P41438, (Rat) Q62866
Entrez Gene ID: (Mouse) 20509, (Rat) 29723
folic acid binding
folic acid transporter activity
reduced folate carrier activity
antiporter activity
methotrexate transporter activity
transmembrane transporter activity
xenobiotic transporter activity
cyclic-GMP-AMP binding
vitamin transmembrane transporter activity
cyclic-GMP-AMP transmembrane transporter activity
drug transmembrane transport
female pregnancy
response to xenobiotic stimulus
response to toxic substance
folic acid transport
vitamin transport
methotrexate transport
transmembrane transport
anion transmembrane transport
reduced folate transmembrane transport
cyclic-GMP-AMP transmembrane import across plasma membrane
positive regulation of cGAS/STING signaling pathway
folic acid import into cell
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
