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产品信息
PA5-50717
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:200-1:1,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:25-1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues near the C terminal of human solute carrier family 22 (organic anion/urate transporter), member 12 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.2 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636169 |
产品详细信息
The antibody detects endogenous levels of total SLC22A12 protein.
靶标信息
SLC22A12 is required for efficient urate re-absorption in the kidney. SLC22A12 regulates blood urate levels. SLC22A12 mediates saturable urate uptake by facilitating the exchange of urate against organic anions.The protein encoded by this gene is a urate transporter and urate-anion exchanger which regulates the level of urate in the blood. This protein is an integral membrane protein primarily found in kidney. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Organic anion transporter 4-like protein; Renal-specific transporter; RST; solute carrier family 22 (organic anion/cation transporter), member 12; solute carrier family 22 (organic anion/urate transporter), member 12; Solute carrier family 22 member 12; URAT1; Urate anion exchanger 1; urate transporter 1; Urate:anion antiporter SLC22A12
基因别名: OAT4L; OATL4; RST; SLC22A12; UNQ6453/PRO34004; URAT1
UniProt ID: (Human) Q96S37
Entrez Gene ID: (Human) 116085
分子生物学功能:
secondary carrier transporter
