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Invitrogen
SLC34A1 Polyclonal Antibody
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产品信息
PA5-89336
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-103 of human SLC34A1
偶联物
形式
Liquid
浓度
4.1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: MLSYGERLGS PAVSPLPVRG GHVMRGTAFA YVPSPQVLHR IPGTSAYAFP SLGPVALAEH TCPCGEVLER HEPLPAKLAL EEEQKPESRL VPKLRQAGAM LLK; Positive Samples: Mouse brain; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals. The brush-border membrane Na+/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na(+)/P(i) cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells. NPT2 gene expression is crucial for PTH effects on renal P(i) handling. However, renal expression of the sodium/phosphate cotransporter gene, NPT2, is not required for regulation of renal 1 alpha-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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