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Alomone Labs, LTD
SLC3A2 (CD98) (extracellular) Polyclonal Antibody
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SLC3A2 (CD98) (extracellular) Antibody (ANT-192-200UL) in IHC (F)
Expression of SLC3A2 (CD98) in mouse hippocampus Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-SLC3A2 (CD98) (extracellular) Antibody (#ANT-192) (1:300), followed by goat anti-rabbit-AlexaFluor-488. A. Staining in the hippocampal CA1 region showed SLC3A2 (CD98) immunoreactivity (green), in pyramidal neurons (vertical arrows) and in interneurons (horizontal arrow). B. ... View More
产品信息
ANT-192-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide CEDNVPDPKDVQEK, corresponding to amino acid residues 278-291 of mouse TMEM175. Luminal, 4th loop.
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: CEDNVPDPKDVQEK
Reconstitution: 50 uL double distilled water (DDW). The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; 4F2hc; Amino acid transporter heavy chain SLC3A2; antigen defined by monoclonal antibody 4F2, heavy chain; antigen identified by monoclonal antibodies 4F2; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; CD98; CD98 antigen; CD98 heavy chain; Lymphocyte activation antigen 4F2 large subunit; monoclonal antibody 44D7; slc3a2 {ECO:0000312|RGD:3073}; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; Solute carrier family 3 member 2; solute carrier family 3, member 2; type II transmembrane protein
基因别名: 4F2; 4F2HC; 4T2HC; AI314110; CD98; CD98HC; Ly-10; Ly-m10; Ly10; MDU1; Mgp-2hc; NACAE; SLC3A2
UniProt ID: (Human) P08195, (Mouse) P10852, (Rat) Q794F9
Entrez Gene ID: (Human) 6520, (Mouse) 17254, (Rat) 50567
