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产品信息
PA5-50630
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:25-1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues near the N terminal of human solute carrier family 4 (anion exchanger), member 1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636083 |
产品详细信息
The antibody detects endogenous levels of total SLC4A1 protein.
靶标信息
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kDa protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AE 1; Anion exchange protein 1; anion exchanger 1; anion exchanger-1; Band 3 anion transport protein; CAMP; CD233; Diego blood group; erythrocyte membrane protein band 3; erythroid anion exchange protein; Froese blood group; MGC116750; MGC116753; MGC126619; MGC126623; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); Solute carrier family 4 member 1; solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; Swann blood group; Waldner blood group; Wright blood group; ZNF828
基因别名: AE1; BND3; CD233; CHC; DI; EMPB3; EPB3; FR; RTA1A; SAO; SLC4A1; SPH4; SW; WD; WD1; WR
UniProt ID: (Human) P02730
Entrez Gene ID: (Human) 6521
分子生物学功能:
secondary carrier transporter
actin binding
inorganic anion exchanger activity
protein binding
protein C-terminus binding
anion transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
anion:anion antiporter activity
enzyme binding
ankyrin binding
protein homodimerization activity
protein anchor
