Sequence homology: Cow: 86%; Dog: 79%; Horse: 86%; Human: 100%; Pig: 79%; Rabbit: 86%; Sheep: 86%
SLIRP (SRA stem-loop interacting RNA binding protein) is expressed in normal and tumor tissues, but the majority of the endogenous SLIRP resides in the mitochondria. SLIRP may regulate mitochondrial functions and has the potential to shut down estrogen in breast cancer cells and testosterone in prostate cancer cells. SLIRP has also been shown to turn down genes involved in energy metabolism.
蛋白别名: SRA stem-loop-interacting RNA-binding protein, mitochondrial
基因别名: C14orf156; DC23; DC50; PD04872; SLIRP
UniProt ID: (Human) Q9GZT3
Entrez Gene ID: (Human) 81892