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Invitrogen
SMC2 Polyclonal Antibody
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SMC2 Antibody (PA1-24675) in WB
Western blot analysis of SMC2 using whole cell lysate (90µg) from mock transfected (E) or SMC2 transfected (T) HEK293T cells. Samples were probed with a SMC2 polyclonal antibody (Product # PA1-24675) at a dilution of 0.1µg/ml. Detection was performed using chemiluminescence with a 10 minute exposure.
产品信息
PA1-24675
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a portion of human structural maintenance of chromosomes 2 encoded within exon 22 (LocusLink ID 10592).
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA1-24675 detects SMC2 from human samples. PA1-24675 is expected to cross react with mouse and Xenopus laevis due to sequence homology.
PA1-24675 has been successfully used in Western blot procedures.
The PA1-24675 immunogen is a synthetic peptide corresponding to a portion of human structural maintenance of chromosomes 2 encoded within exon 22 (LocusLink ID 10592).
靶标信息
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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