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FIGURE: 1 / 5
SMYD1 Antibody (PA5-96108) in WB
Western blot analysis of SMYD1 in extracts of various cell lines. Samples were incubated with SMYD1 Polyclonal antibody (Product # PA5-96108) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-96108
Applications
Tested Dilution
Publications
产品规格
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human SMYD1.
Conjugate
Unconjugated
形式
Liquid
浓度
0.74 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2807910
Product Specific Information
Immunogen sequence: MTIGRMENVE VFTAEGKGRG LKATKEFWAA DIIFAERAYS AVVFDSLVNF VCHTCFKRQE KLHRCGQCKF AHYCDRTCQK DAWLNHKNEC SAIKRYGKVP NENIRLAARI MWRVEREGTG LTEGCLVSVD DLQNHVEHFG EEEQKDLRVD VDTFLQYWPP QSQQFSMQYI SHIFGVINCN GFTLSDQRGL QAVGVGIFPN LGLVNHDCWP NCTVIFNNGN HEAVKSMFHT QMRIELRALG KISEGEELTV SYIDFLNVSE ERKRQLKKQY YFDCTCEHCQ KKLKDDLFLG VKDNPKPSQE VVKEMIQFSK DTLEKIDKAR SEGLYHEVVK LCRECLEKQE PVFADTNIYM; Positive Samples: Raji, MCF7, Mouse stomach, Rat heart, Rat stomach; Cellular Location: Cytoplasm, Nucleus
Target Information
Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: CD8 beta opposite; CD8b-opposite; CD8beta opposite strand; Histone-lysine N-methyltransferase SMYD1; m-BOP; SET and MYND domain-containing protein 1; Zinc finger protein BOP; zinc finger, MYND domain containing 18
Gene Aliases: 4632404M21Rik; BOP; C78565; KMT3D; SMYD1; ZMYND18; ZMYND22
UniProt ID: (Human) Q8NB12, (Mouse) P97443
Entrez Gene ID: (Human) 150572, (Mouse) 12180, (Rat) 297333
Molecular Function:
histone modifying enzyme
chromatin remodeling
transcription, DNA-templated
heart development
positive regulation of myotube differentiation
histone lysine methylation
skeletal muscle cell differentiation
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
methylation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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