Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
SMYD3 Recombinant Rabbit Monoclonal Antibody (4H2L28)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 2
SMYD3 Antibody (702519) in WB
Knockdown of SMYD3 was achieved by transfecting HeLa cells with SMYD3 specific siRNA (Silencer® select Product # s34865 and Product # s34863). Western blot analysis (Fig a) was performed using nuclear enriched lysates from the SMYD3 knock down cells (lane 3), non-specific scrambled siRNA transfected cells (lane 2) and untransfected cells (lane 1). The blots were probed with Anti-SMYD3 Recombinant Rabbit Monoclonal Antibody (Product # 702519, 1-2 µg/mL) and Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (P... View More
产品信息
702519
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4H2L28
抗原
Protein corresponding to human SMYD3 (aa1-aa428)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2692254
产品详细信息
This antibody is predicted to react with Monkey, Rat, Mouse
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
SMYD3 (histone-lysine N-methyltransferase) methylates Lys-4 of histone H3 and Lys-5 of histone H4. It induces di- and tri-methylation. SMYD3 plays an important role in transcriptional activation as a member of an RNA polymerase complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: bA74P14.1 (novel protein); Histone-lysine N-methyltransferase SMYD3; SET and MYND domain-containing protein 3; Zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; zinc finger, MYND domain containing 1
基因别名: bA74P14.1; KMT3E; SMYD3; ZMYND1; ZNFN3A1
UniProt ID: (Human) Q9H7B4
Entrez Gene ID: (Human) 64754
nucleosome assembly
negative regulation of protein kinase activity
myotube cell development
positive regulation of peptidyl-serine phosphorylation
histone lysine methylation
establishment of protein localization
positive regulation of transcription from RNA polymerase II promoter
cellular response to dexamethasone stimulus
