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Exalpha
SNAP Monoclonal Antibody (16D1)
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产品信息
X1024
产品规格
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
16D1
抗原
Recombinant human alpha SNAP
偶联物
形式
Liquid
浓度
0.5-2 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Positive control: Rat brain.
靶标信息
SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs ( SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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