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SNAP25 Antibody (711023) in WB
Western blot analysis was performed on Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Rat Brain (Lane 2) and Whole cell extracts (30 µg lysate)of SH SY5Y (Lane 3), Neuro-2a (Lane 4), IMR32 (Lane 5), U-87 MG (Lane 6), KARPAS 299 (Lane 7) and PC-12 (Lane 8). The blots were probed with Anti-Synaptosomal Associated Protein 25/SNAP25 Recombinant Rabbit Polyclonal Antibody (Product # 711023, 1-2 µg/mL). A 25 kDa band corresponding to Synaptosomal Associated Protein 25/SNAP25 was observed only in Brain tissue and PC-12. The blots were de... View More
产品信息
711023
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
抗原
Peptides corresponding to human SynaptosoSNAP25 [1) aa37-aa55, 2) aa168-aa186]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2692267
产品详细信息
This antibody is predicted to react with Horse, Pig, Rabbit
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
靶标信息
SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ALMS1; blind drunk; CG17676; CG17884; CG40452; Dmel CG40452; Dmel_CG40452; FLJ23079; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; snp25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
基因别名: bA416N4.2; Bdr; CMS18; dJ1068F16.2; GENA70; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP-25a; SNAP-25B; SNAP25; sp; SUP
UniProt ID: (Human) P60880, (Rat) P60881, (Mouse) P60879
Entrez Gene ID: (Human) 6616, (Rat) 25012, (Mouse) 20614
neurotransmitter uptake
chemical synaptic transmission
neurotransmitter secretion
locomotory behavior
associative learning
regulation of neuron projection development
glutamate secretion
synaptic vesicle exocytosis
synaptic vesicle docking
synaptic vesicle priming
synaptic vesicle fusion to presynaptic active zone membrane
regulation of insulin secretion
long-term synaptic potentiation
exocytosis
axonogenesis
long-term memory
endosomal transport
growth hormone secretion
sleep
positive regulation of insulin secretion
positive regulation of hormone secretion
calcium ion-regulated exocytosis of neurotransmitter
regulation of synapse assembly
regulation of establishment of protein localization
potassium ion transmembrane transport
regulation of ion transmembrane transport
