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This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
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Immunogen sequence: MVLSGCAIIV RGQPRGGPPP ERQINLSNIR AGNLARRAAA TQPDAKDTPD EPWAFPAREF LRKKLIGKEV CFTIENKTPQ GREYGMIYLG KDTNGENIAE SLVAEGLATR REGMRANNPE QNRLSECEEQ AKAAKKGMWS EGNGSHTIRD LKYTIENPRH FVDSHHQKPV NAIIEHVRDG SVVRALLLPD YYLVTVMLSG IKCPTFRREA DGSETPEPFA AEAKFFTESR LLQRDVQIIL ESCHNQNILG TILHPNGNIT; Positive Samples: HeLa, Jurkat, HL-60, MCF7, 293T, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Melanosome, Nucleus
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 100 kDa coactivator; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100 co-activator; p100 EBNA2 co-activator; p105 coactivator; SND p102; SND1-BRAF fusion; staphylococcal nuclease domain containing 1; Staphylococcal nuclease domain-containing protein 1; testis tissue sperm-binding protein Li 82P; Tudor domain-containing protein 11; Tudor-SN; TudorSN
基因别名: AL033314; p100; SND p102; SND1; TDRD11; Tudor-SN
UniProt ID: (Human) Q7KZF4, (Rat) Q66X93, (Mouse) Q78PY7
Entrez Gene ID: (Human) 27044, (Rat) 64635, (Mouse) 56463