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SND1 Antibody (MA5-49230) in ICC/IF
Immunocytochemistry analysis of SND1 in PC-3 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in SND1 Monoclonal antibody (Product # MA5-49230) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Mouse IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate for t... View More
产品信息
MA5-49230
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
6G3B4
抗原
E.coli-derived human SND1 recombinant protein (Position: Q20-D204).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3074888
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
靶标信息
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 100 kDa coactivator; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100 co-activator; p100 EBNA2 co-activator; p105 coactivator; SND p102; SND1-BRAF fusion; staphylococcal nuclease domain containing 1; Staphylococcal nuclease domain-containing protein 1; testis tissue sperm-binding protein Li 82P; Tudor domain-containing protein 11; Tudor-SN; TudorSN
基因别名: AL033314; p100; SND p102; SND1; TDRD11; Tudor-SN
UniProt ID: (Human) Q7KZF4, (Rat) Q66X93, (Mouse) Q78PY7
Entrez Gene ID: (Human) 27044, (Rat) 64635, (Mouse) 56463
