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Invitrogen
SNURF Polyclonal Antibody
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产品信息
PA5-66794
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LRRTTEQHVPE VEVQVKRRRT ASLSNQECQL YPRRS
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 94%.
靶标信息
SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Sm protein D; Sm protein N; Sm-D; Sm-N; Small nuclear ribonucleoprotein-associated protein N; snRNP-N; SNRPN upstream reading frame protein; Tissue-specific-splicing protein
基因别名: HCERN3; SMN; SNRPN; SNURF
UniProt ID: (Human) Q9Y675
Entrez Gene ID: (Human) 8926
