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Invitrogen
SNX8 Monoclonal Antibody (3B6)
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产品信息
MA5-24455
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3B6
抗原
SNX8 (AAH21565, 1 a.a. ~ 465 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide Sequence: MTGRAMDPLP AAAVGAAAEA EADEEADPPA SDLPTPQAIE PQAIVQQVPA PSRMQMPQGN PLLLSHTLQE LLARDTVQVE LIPEKKGLFL KHVEYEVSSQ RFKSSVYRRY NDFVVFQEML LHKFPYRMVP ALPPKRMLGA DREFIEARRR ALKRFVNLVA RHPLFSEDVV LKLFLSFSGS DVQNKLKESA QCVGDEFLNC KLATRAKDFL PADIQAQFAI SRELIRNIYN SFHKLRDRAE RIASRAIDNA ADLLIFGKEL SAIGSDTTPL PSWAALNSST WGSLKQALKG LSVEFALLAD KAAQQGKQEE NDVVEKLNLF LDLLQSYKDL CERHEKGVLH KHQRALHKYS LMKRQMMSAT AQNREPESVE QLESRIVEQE NAIQTMELRN YFSLYCLHQE TQLIHVYLPL TSHILRAFVN SQIQGHKEMS KVWNDLRPKL SCLFAGPHST LTPPCSPPED GLCPH
靶标信息
Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNXs partially associate with cellular membranes, despite their hydrophilic nature. SNX8 is an ortholog of a yeast protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Sorting nexin-8
基因别名: Mvp1; SNX8
UniProt ID: (Human) Q9Y5X2
Entrez Gene ID: (Human) 29886, (Rat) 288504
