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Invitrogen
SOX7 Polyclonal Antibody
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SOX7 Antibody (PA5-80055) in WB
Western blot analysis of SOX7 in Lane 1: rat brain tissue lysate, Lane 2: human placenta tissue lysate, Lane 3: rat lung tissue lysate, Lane 4: rat testis tissue lysate, Lane 5: HeLa whole cell lysate, Lane 6: A549 whole cell lysate, Lane 7: HEPG2 whole cell lysate, Lane 8: SMMC whole cell lysate, Lane 9: NEURO whole cell lysate using 40-50 µg per well. Sample was incubated with SOX7 (Product # PA5-80055) at a dilution of 0.5 µg/mL.
产品信息
PA5-80055
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human SOX7 (370-388aa LISVLADATATYYNSYSVS).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, Human Placenta Tissue, Rat Lung Tissue, Rat Testis Tissue, HELA whole cell, A549 whole cell, HEPG2 whole cell, SMMC whole cell, NEURO whole cell.
靶标信息
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC10895; mSOX7; SRY (sex determining region Y)-box 7; SRY box 7; SRY-box containing gene 7; Transcription factor SOX-7
基因别名: Sox-7; SOX7
UniProt ID: (Human) Q9BT81, (Mouse) P40646
Entrez Gene ID: (Human) 83595, (Mouse) 20680, (Rat) 290317
transcription factor activity, sequence-specific DNA binding
protein binding
transcription regulatory region DNA binding
DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
sequence-specific DNA binding
molecular_function
HMG box transcription factor
endoderm formation
transcription, DNA-templated
negative regulation of cell proliferation
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of transcription, DNA-templated
regulation of canonical Wnt signaling pathway
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
biological_process
