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Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化 (IHC) |
1:200-1:500 | - |
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant protein corresponding to Human SPINK5 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.2 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2647862 |
Immunogen sequence: QQEERARAKA KREAAKEICS EFRDQVRNGT LICTREHNPV RGPDGKMHGN KCAMCASVFK LEEEEKKNDK EEKGKVEAEK VKREAVQELC SEYRHYVRNG RLPC
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 73%.
Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor which protects mucous epithelia against microbial attack and inflammation. LEKTI is a marker of epithelial differentiation and expresses strongly in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia. Defects in SPINK5, the gene encoding LEKTI, are the cause of Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever and other conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665; ISK5; LEKTI; Lympho-epithelial Kazal-type-related inhibitor; lymphoepithelial Kazal-type-related inhibitor; Serine protease inhibitor Kazal-type 5
基因别名: LEKTI; LETKI; NETS; NS; SPINK5; VAKTI
UniProt ID: (Human) Q9NQ38
Entrez Gene ID: (Human) 11005
分子生物学功能:
protease inhibitor
