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产品信息
PA5-50656
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:25-1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to a region derived from internal residues of human epididymal peptidase inhibitor |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.4 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636108 |
产品详细信息
The antibody detects endogenous levels of total EPPIN protein.
靶标信息
Eppin, an epididymal protease inhibitor, belongs to the WFDC family and to the telomeric cluster. The gene encoding the protein is localized to chromosome 20q12-q13 in centromeric and telomeric clusters. It expresses three mRNAs encoding two isoforms of a cystine-rich protein that contains Kunitz-type and WAP-type (four disulfide core) protease inhibitor consensus sequences. The mouse gene lies in a cluster of putative Eppin-like genes on mouse chromosome 2. Following ejaculation, Eppin is bound to semenogelin in seminal plasma and on human spermatozoa. This complex of Eppin and Semenogelin can provide antimicrobial activity for spermatozoa. It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract. Eppin, which is a secreted protein, is expressed in epididymis and testis.
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生物信息学
蛋白别名: Cancer/testis antigen 71; cancer/testis antigen 72; CT71; Epididymal protease inhibitor; Eppin; EPPIN1; EPPIN2; EPPIN3; Protease inhibitor WAP7; serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin); Serine protease inhibitor-like with Kunitz and WAP domains 1; serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin); WAP four-disulfide core domain protein 7
基因别名: 1700024E17Rik; CT71; CT72; dJ461P17.2; EPPIN; SPINLW1; WAP7; WFDC7
UniProt ID: (Human) O95925, (Mouse) Q9DA01
Entrez Gene ID: (Human) 57119, (Mouse) 75526
