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Invitrogen
SPO11 Polyclonal Antibody
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SPO11 Antibody (PA5-99106) in WB
Western Blot analysis of SPO11 using a SPO11 Polyclonal antibody (Product # PA5-99106) at a concentration of 5.8 µg/mL. Positive WB detected in: Jurkat whole cell lysate, Raji whole cell lysate, HepG2 whole cell lysate, 293T whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 45 kDa.
产品信息
PA5-99106
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Meiotic recombination protein SPO11 protein (28-109AA)
偶联物
形式
Liquid
浓度
2.87 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cancer/testis antigen 35; CT35; Meiotic recombination protein SPO11; MGC39953; spermatogenesis associated 43; SPO11 meiotic protein covalently bound to DSB homolog
基因别名: CT35; SPATA43; SPO11; TOPVIA
UniProt ID: (Human) Q9Y5K1
Entrez Gene ID: (Human) 23626
