Invitrogen

SPOCK1 Polyclonal Antibody

Name: SPOCK1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-52435

查看其他5个SPOCK1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (4)

SPOCK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SPOCK1 Antibody (PA5-52435) in IHC (P)

Immunohistochemistry analysis of SPOCK1 in human tonsil. Samples were incubated with SPOCK1 polyclonal antibody (Product # PA5-52435). Shows strong cytoplasmic positivity in non-germinal center cells.

SPOCK1 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

Immunogen image

Immunogen Image SPOCK1 Polyclonal Antibody

产品信息

PA5-52435

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human SPOCK1. Recombinant protein control fragment (Product #RP-88691).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2647880

产品详细信息

Immunogen sequence: FKDGKLSNNE WCYCFQKPGG LPCQNEMNRI QKLSKGKSLL GAFIPRCNEE GYYKATQCHG STGQCWCVDK YGNELAGSRK QGAVSCEEEQ ETSGDFGSGG

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.

靶标信息

SPOCK1, also known as Testican-1, is a gene located on chromosome 5q31.2, encoding a member of the proteoglycan family characterized by containing multiple domains that facilitate interactions with other extracellular matrix proteins. SPOCK1 is primarily expressed in various tissues, including the brain and reproductive organs, where it plays crucial roles in modulating cell adhesion, migration, and matrix remodeling. Functionally, SPOCK1 contributes to the regulation of extracellular matrix composition, influencing processes such as tissue development and wound healing. In the context of cancer, SPOCK1 is often upregulated, promoting tumor progression and metastasis by enhancing cancer cell motility and invasiveness. Its involvement in these pathological mechanisms makes SPOCK1 a potential biomarker for cancer prognosis and a target for therapeutic intervention. Research continues to unravel SPOCK1's diverse biological activities and its impact on cellular architecture and disease progression.

仅用于科研。不用于诊断过程。未经明确授权不得转售。