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Proteintech
SPOP Polyclonal Antibody
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产品信息
16750-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SPOP Fusion Protein Ag10215 (1-374 aa encoded by BC003385)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSRVPSPPP PAEMSSGPVA ESWCYTQIKV VKFSYMWTIN NFSFCREEMG EVIKSSTFSS GANDKLKWCL RVNPKGLDEE SKDYLSLYLL LVSCPKSEVR AKFKFSILNA KGEETKAMES QRAYRFVQGK DWGFKKFIRR DFLLDEANGL LPDDKLTLFC EVSVVQDSVN ISGQNTMNMV KVPECRLADE LGGLWENSRF TDCCLCVAGQ EFQAHKAILA ARSPVFSAMF EHEMEESKKN RVEINDVEPE VFKEMMCFIY TGKAPNLDKM ADDLLAAADK YALERLKVMC EDALCSNLSV ENAAEILILA DLHSADQLKT QAVDFINYHA SDVLETSGWK SMVVSHPHLV AEAYRSLASA QCPFLGPPRK RLKQS (1-374 aa encoded by BC003385)
靶标信息
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: HIB homolog 1; PDX-1 C-terminal-interacting factor 1; Roadkill homolog 1; speckle type POZ protein; Speckle-type POZ protein
基因别名: AI315626; BTBD32; Pcif1; SPOP; TEF2
UniProt ID: (Human) O43791, (Mouse) Q6ZWS8
Entrez Gene ID: (Human) 8405, (Mouse) 20747, (Rat) 287643
regulation of proteolysis
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription from RNA polymerase II promoter
glucose homeostasis
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of type B pancreatic cell apoptotic process
