Invitrogen

SQRDL Polyclonal Antibody

Name: SQRDL Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-53549
Availability: InStock

高级验证

查看其他7个SQRDL抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (9)
高级验证 (2)

SQRDL Antibody in Immunocytochemistry (ICC/IF)

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SQRDL Antibody (PA5-53549) in ICC/IF

Immunofluorecent analysis of SQRDL in human cell line A549 using SQRDL Polyclonal Antibody (Product # PA5-53549). Staining shows localization to mitochondria.

SQRDL Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SQRDL Antibody in Immunohistochemistry (IHC)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

SQRDL Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of SQRDL was observed specifically in A-549 cells and in HEK293 cells using anti-SQRDL Polyclonal Antibody (Product # PA5-53549) in western blot. The relative expression levels of SQRDL within each cell line is shown using RNA-Seq. {RE}

产品信息

PA5-53549

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human SQRDL. Recombinant protein control fragment (Product #RP-89842).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.30 mg/mL

30 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2647905

产品详细信息

Immunogen sequence: TSPVADAAGW VDVDKETLQH RRYPNVFGIG DCTNLPTSKT AAAVAAQSGI LDRTISVIMK NQTPTKKYDG YTSCPLVTGY NRVILAEFDY KAEPLETFPF DQSKERLSMY LMKADLMPFL YWNMMLRGYW G

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 93%.

靶标信息

SQRDL (Sulfide: quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Although the SQRDL precursor protein displays a molecular weight of 50 kDa, a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during the import of the protein into the mitochondria. SQRDL is one of the enzymes involved in H2S signaling in a discrete population of neurons, oligodendrocytes, and endothelial cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。