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Invitrogen
SQSTM1 Polyclonal Antibody
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产品信息
PA1-18271
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C-terminal residues I(424) G A A L D T I Q Y S K H(436) of human Sequestosome 1 conjugated to the Blue Carrier Protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-18271 detects Sequestosome 1 from human samples. This antibody is expected to cross react with mouse, rat, and bovine Sequestosome 1, due to sequence homology.
PA1-18271 has been successfully used in immunohistochemistry (paraffin) and Western blot procedures.
The PA1-18271 immunogen is a synthetic peptide corresponding to the C-terminal residues I(424) G A A L D T I Q Y S K H(436) of human Sequestosome 1, conjugated to the Blue Carrier Protein.
After reconstitution keep aliquots at -20°C for a higher stability, and at 4°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
Reconstitute with 100 µL of distilled water. Glycerol (1:1) may be added for additional stability.
靶标信息
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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