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Invitrogen
SR-BI Polyclonal Antibody
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产品信息
PA5-19538
产品规格
已发表种属
Bovine
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Mouse Scavenging Receptor SR-BI.
偶联物
形式
Liquid
浓度
0.8-0.9 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
This antibody is predicted to react with human based on sequence homology.
靶标信息
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
