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Invitrogen
SR protein repeat Recombinant Rabbit Monoclonal Antibody (K01_4P49)
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产品信息
MA567547
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_4P49
抗原
A synthesized peptide derived from human SR protein repeat.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol, 150mM NaCl, 0.05% BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
SR proteins are a highly conserved family of arginine/serine-rich, spliceosome-associated phosphoproteins essential for metazoan pre-mRNA splicing. SR proteins act early in splicing by promoting splice site recognition and spliceosome assembly. SR proteins also play a regulatory role because they can determine alternative splice site usage in vivo and in vitro. SR proteins appear to be recruited from nuclear 'speckles', in which they are concentrated to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Delayed-early protein HRS; epididymis secretory protein Li 91; epididymis secretory sperm binding protein; pre-mRNA splicing factor SRp20; Pre-mRNA-splicing factor SRP20; Pre-mRNA-splicing factor SRP40; Pre-mRNA-splicing factor SRP55; Pre-mRNA-splicing factor SRP75; RNA binding protein; Serine/arginine-rich splicing factor 3; Serine/arginine-rich splicing factor 4; Serine/arginine-rich splicing factor 5; Serine/arginine-rich splicing factor 6; SFRS5; Splicing factor, arginine/serine-rich 3; Splicing factor, arginine/serine-rich 4; Splicing factor, arginine/serine-rich 5; Splicing factor, arginine/serine-rich 6; splicing factor, arginine/serine-rich, 20-kD; splicing factor, arginine/serine-rich, 55 kDa; SR splicing factor 4; SR splicing factor 5; SR splicing factor 6; SRP001LB; unnamed protein product
基因别名: B52; HEL-S-91; HRS; SFRS3; SFRS4; SFRS5; SFRS6; SRP20; SRP40; SRP55; SRP75; SRSF3; SRSF4; SRSF5; SRSF6
UniProt ID: (Human) P84103, (Human) Q08170, (Human) Q13243, (Human) Q13247
Entrez Gene ID: (Human) 6428, (Human) 6429, (Human) 6430, (Human) 6431
RNA splicing, via transesterification reactions
regulation of alternative mRNA splicing, via spliceosome
liver development
mRNA splice site selection
mRNA processing
RNA splicing
response to insulin
cellular response to insulin stimulus
positive regulation of RNA splicing
liver regeneration
alternative mRNA splicing, via spliceosome
negative regulation of gene expression
regulation of keratinocyte proliferation
negative regulation of keratinocyte differentiation
negative regulation of mRNA splicing, via spliceosome
positive regulation of epithelial cell proliferation involved in lung morphogenesis
regulation of wound healing
negative regulation of type B pancreatic cell apoptotic process
RNA processing
mRNA export from nucleus
primary miRNA processing
regulation of mRNA splicing, via spliceosome
mRNA transport
cellular response to leukemia inhibitory factor
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