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Peptide sequence: GFGYDMSTPN APLHYYETVR MAAIKESWTH NIQREKEFLR KLVKARVITD
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Multiple transcript variants encoding several different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: alpha 2,3-sialyltransferase III; Alpha 2,3-ST 3; alpha-2,3-sialyltransferase II; Beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; Gal beta-1,3(4)GlcNAc alpha-2,3 sialyltransferase; mental retardation, non-syndromic, autosomal recessive, 12; N-acetyllactosaminide alpha-2,3-sialyltransferase; Sialyltransferase 6; sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase); ST3Gal III; ST3GalIII; ST3N
Gene Aliases: EIEE15; MRT12; SIAT6; ST3GAL3; ST3GALII; ST3GalIII; ST3N
UniProt ID: (Human) D3DPX8
Entrez Gene ID: (Human) 6487
Molecular Function:
transferase
metabolite interconversion enzyme
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