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Immunogen sequence: LYILKLNYTT EECDMKKMHY VDPDHVKRAQ KYAQQVLQKE CRPKFAKTSM ALLFEHRYSV DLLPFVQKAP KDSEAESKYD PPFGFRKFSS KVQTLLELLP EHDLPEHLKA KTCRRCVVIG S; Positive Samples: BT-474, U-251MG, SH-SY5Y, Mouse brain, Rat brain; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha 2,3-sialyltransferase V; CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Ganglioside GM3 synthase; GM3 synthase; GM3-specific sialytransferase; Lactosylceramide alpha-2,3-sialyltransferase; mST3Gal V; Sialyltransferase 9; sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase); sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase); ST3 beta-galactoside alpha-23-sialyltransferase 5; ST3Gal V; ST3GalV
基因别名: 3S-T; [a]2; GM3S; SATI; SIAT9; SIATGM3S; ST3GAL5; ST3GalV; UNQ2510/PRO5998
UniProt ID: (Human) Q9UNP4, (Rat) Q68G12, (Mouse) O88829
Entrez Gene ID: (Human) 8869, (Rat) 83505, (Mouse) 20454