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Proteintech
ST6GAL1 Polyclonal Antibody
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产品信息
14355-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ST6GAL1 Fusion Protein Ag5705 (60-406 aa encoded by BC040009)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Western blot analysis of human liver using this antibody detects both isoforms between 43-50 kDa. Higher molecular weight of bands around 50-70 kDa can also be observed with unknown reason.
Immunogen sequence: SQSVSSSST QDPHRGRQTL GSLRGLAKAK PEASFQVWNK DSSSKNLIPR LQKIWKNYLS MNKYKVSYKG PGPGIKFSAE ALRCHLRDHV NVSMVEVTDF PFNTSEWEGY LPKESIRTKA GPWGRCAVVS SAGSLKSSQL GREIDDHDAV LRFNGAPTAN FQQDVGTKTT IRLMNSQLVT TEKRFLKDSL YNEGILIVWD PSVYHSDIPK WYQNPDYNFF NNYKTYRKLH PNQPFYILKP QMPWELWDIL QEISPEEIQP NPPSSGMLGI IIMMTLCDQV DIYEFLPSKR KTDVCYYYQK FFDSACTMGA YHPLLYEKNL VKHLNQGTDE DIYLLGKATL PGFRTIHC (60-406 aa encoded by BC040009 )
靶标信息
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Alpha 2,6-ST 1; B-cell antigen CD75; beta galactoside alpha 2,6 sialyltransferase 1; Beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; Sialyltransferase 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase); Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase); ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI
基因别名: AW742324; SIAT1; St6gal; St6Gal-I; ST6GAL1; ST6GalI; ST6N
UniProt ID: (Human) P15907, (Mouse) Q64685, (Rat) P13721
Entrez Gene ID: (Human) 6480, (Mouse) 20440, (Rat) 25197
N-acetylneuraminate metabolic process
humoral immune response
oligosaccharide metabolic process
O-glycan processing
protein N-linked glycosylation via asparagine
positive regulation of mononuclear cell proliferation
response to ethanol
negative regulation of chemotaxis
sialylation
regulation of substrate adhesion-dependent cell spreading
protein sialylation
negative regulation of macrophage apoptotic process
protein glycosylation
